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Among exposed to smoke at baseline, the mean E2 levels was 16.5 pmol/l, resulting in a difference of 16.512.4 = 4.1 pmol/l (33.1%), more due to exposure to tobacco smoking ( p = 0.04)

With 65%RH being required to maintain the tobaccos moisture content, any air introduced with a relative humidity of 24% would lead to moisture loss from the tobacco without correct humidification

There is every reason to believe such substitution would also be beneficial for the fetus